When you are using beads try using a larger hook, like a #8 Wide gap. Wide gap hooks a specifically designed for situations such as bead fishing. I would also use a slightly stronger leader, try using 6lb-8lb leader in water that isn't clear. The strong leader usually has less stretch and will provide a better hook set. Since you are using a 10'6" rod I would set the hook as hard as possible since you don't create the speed a 13ft rod would, also when you set the hook try to set it straight up. Like NADO said, make sure you don't have any slack in your line, the smallest amount of slack will reduce your hook ups significantly. As for knots, I would only suggest using the snell if you are using a hook which has an offset shank, if you use this knot on a straight shank hook you will actually decrease your effectiveness of the hook.
Goodluck!